3 QUESTIONS ON... Why Addressing Hearing Loss in Survivors of Childhood Cancers Matters

Hearing Loss in Cryptococcal Meningitis Survivors

On Explaining Existence 3 Why Questions

What are the limits of physics’ explanatory power? Can physics explain everything? In this paper I discuss a somewhat broader question: can physics explain existence itself? I argue that genuinely ultimate explanations—those that really explain everything—involve the most basic and most general elements of logic. Such explanations cannot be done within physics unless physics undergoes a methodo...

Hearing loss after platinum treatment is irreversible in noncranial irradiated childhood cancer survivors.

Cisplatin and carboplatin are effective antineoplastic agents. They are also considered to be potentially highly ototoxic. To date, no long-term follow-up data from well-documented cohorts with substantial numbers of childhood cancer survivors (CCS) with platinum-related hearing loss are available. Therefore, in this study, we studied the reversibility of ototoxicity from discontinuation of tre...

Long-term survivors of childhood cancers in the United States.

PURPOSE To estimate the number of individuals in the United States diagnosed with cancer as children (ages 0-19 years) as of 2005, with a focus on those surviving for >30 years. METHODS To estimate the national prevalence of survivors of childhood cancers, we used data from the Surveillance Epidemiology and End Results program from 1975 to 2004. Long-term childhood cancer survivors, diagnosed...

Endocrine complications in long-term survivors of childhood cancers.

Endocrine disturbances are among the most frequently reported complications in childhood cancer survivors, affecting between 20 and 50% of individuals who survive into adulthood. Most endocrine complications are the result of prior cancer treatments, especially radiotherapy. The objective of the present review is to discuss the main endocrine complications observed in this population, including...